KNCV Tuberculosis Foundation

KNCV Tuberculosis Foundation is dedicated to fighting TB worldwide and to strengthening health systems against TB.


Our vision is: A world free of tuberculosis.


Our mission is: The global elimination of TB through the development and implementation of effective, efficient and sustainable TB control strategies.

The six principles that guide our work:

  1. Base the KNCV strategy on the Universal Health Coverage agenda;

  2. Consider the legal and ethical issues of TB care and a human rights-based approach;

  3. Identify the greatest impact at the lowest cost and least effort;

  4. Ensure country ownership and country-specific design of interventions;

  5. Value and build partnerships at all levels;

  6. Ensure transfer of knowledge as an integral part of our technical assistance

KNCV Tuberculosis Foundation is the lead partner in the USAID project Challenge TB, the largest TB control project in the world. For the fourth time in a row we are leading this flagship project, which is implemented by a coalition consisting of, next to KNCV, American Thoracic Society (ATS), FHi 360, The Union, Japan Anti-Tuberculosis Association (JATA),  Management Sciences for Health (MSH), WHO Stop TB Department, PATH and Interactive Research and Development (IRD).


Challenge TB currently works in 22 countries in Eastern Europe, Central Asia, East Asia and Africa: Ukraine, Afghanistan, Kyrgyzstan, Tajikistan, Bangladesh, Burma, Cambodia, India, Indonesia, Vietnam, Botswana, DR Congo, East Africa Region, Ethiopia, Malawi, Mozambique, Namibia, Nigeria, South Sudan, Tanzania and Zimbabwe.

Challenge TB Strategies and principles
The Challenge TB partners operate using a framework which has four strategies:
> Engage stakeholders, including national TB programs, new partners and individuals, and especially youth.
> Empower key decision-makers, people affected by TB, and marginalized and vulnerable populations.
> Evaluate interventions, measure quality, develop evidence, and implement best practices.
> Expand on the provider and service range, and remove barriers to access.

In addition, there are four principles to which Challenge TB partners are committed: quality-focused deliverables and technical assistance; locally owned and generated innovations, research and solutions; innovative approaches, technologies, tools and thinkers; and a patient-centered focus throughout our work.

Objectives and intervention areas
Challenge TB has three objectives, each with several focus areas for interventions:

Objective 1: Improved access to high-quality patient-centered TB, DR-TB & TB/HIV services
By improving the enabling environment
By ensuring a comprehensive, high quality diagnostic network
By strengthening patient-centered care and treatment.

Objective 2: Prevent transmission and disease progression
By targeted screening for active TB
By implementing infection control measures
By managing latent TB infection.

Objective 3: Strengthen TB service delivery platforms
By enhancing political commitment & leadership
By strengthening drug & commodity management systems
By ensuring quality data, surveillance and monitoring & evaluation
By supporting human resource development
By building comprehensive partnerships & informed community engagement.